Improving Treatment Outcomes for Tuberculosis

Improving Treatment Outcomes for Tuberculosis

Major issues are currently associated with Tuberculosis (TB) treatment, particularly in patients infected by Multidrug Resistant Tuberculosis/Extensively Drug Resistant Tuberculosis (mdr-TB/XDR-TB) resistant mycobacteria. A new threat recently reported in various Asian countries is totally Drug Resistant Tuberculosis (TDR). The presence of such Mycobacterium tuberculosis strains is disturbing a...

improving outcomes for adolescents with drug-resistant tuberculosis

Improving outcomes for multidrug-resistant tuberculosis: aggressive regimens prevent treatment failure and death.

BACKGROUND Evidence is sparse regarding the optimal construction of regimens to treat multidrug-resistant (MDR) tuberculosis disease due to strains of Mycobacterium tuberculosis resistant to at least both isoniazid and rifampin. Given the low potency of many second-line antituberculous drugs, we hypothesized that an aggressive regimen of at least 5 likely effective drugs during the intensive ph...

Pleural Tuberculosis and its Treatment Outcomes

Purpose: To evaluate the incidence, treatment and clinical outcomes of tuberculosis pleuritis at a hospital in the state of Penang, Malaysia. Methods: A retrospective study was conducted in Hospital of Penang, Malaysia. Patient records were reviewed retrospectively to identify patients with confirmed diagnosis of tuberculous pleuritis from January 2006 to December 2008. Chest x-ray (CXR) and pl...

Improving specific disease outcomes through a One Health approach--tuberculosis.

Early discoveries in the field of tuberculosis more than a century ago indicated that the success of disease control in human populations would depend on the success of control measures in animals, and vice versa. Recognising the zoonotic importance of a cattle-derived pathogen was the beginning of the eradication of bovine tuberculosis from most of the cattle population in Europe. It was a cos...